Archives of Disease in Childhood (ADC) is an international peer-reviewed journal specialising in child health, covering the perinatal period through to adolescence. As an official journal of the Royal College of Paediatrics and Child Health, ADC provides paediatricians with the most recent, relevant and original research reports, commentaries, clinical and policy reviews, and education.

Every 3 months ADC publishes a Drug Therapy section which looks at different aspects of paediatric clinical pharmacology. Listed below are the five most cited articles in 2018 - 2019:

  • Developing a paediatric drug formulary for the Netherlands
  • Systematic review of the toxicity of short-course oral corticosteroids in children
  • Variation in paediatric hospital antibiotic guidelines in Europe
  • C-reactive protein point-of-care testing in acutely ill children: a mixed methods study in primary care
  • An increase in accident and emergency presentations for adverse events following immunisation after introduction of the group B meningococcal vaccine: an observational study

Read these and others here.
Members of the ESDPPP are encouraged to submit to the ADC Drug Therapy section. All articles across the pharmacology spectrum, from basic science (pharmacokinetics, pharmacodynamics), to randomised controlled trials, formulations, drug safety/pharmacovigilance, pharmacogenomics, pharmaco-epidemiology, and ethics/legal issues, will be considered if they have relevance to paediatrics.
ADC also publishes a drug therapy update section in the education section, that features reviews on many areas of therapeutics in paediatrics.

The next ESDPPP conference will be taking place in in Liverpool, UK, in 2021, and all abstracts accepted will be published in a supplement in ADC following the meeting.
Members who wish to consider writing a review article should contact Dan Hawcutt first ( 

Current articles from the ADC Journal

Mixed messages To use the emergency department vernacular, this family was a ‘frequent flyer’. If you took the time to check the entries from 54/55 one of the three children would attend on a near weekly basis. Closer scrutiny would also have shown that most attendances were in the mid to late evening. It would have taken little extra effort to conclude that the symptoms were rarely distressing for the children: an URI, a sprained ankle, a barely discernible scratch from an errant kite in Central. Never more than an advice and acetaminophen job. Of more concern (at least so was said by the interns retrospectively) was that it was always the mother, E, in her early 20 s who came, her husband, stolidly, ‘at home entertaining the others with cookies and the latest Disney cartoons on the colour TV inherited from his own parents as a wedding gift’....
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'Crowded paediatrics
It is a simplification, but the traditional ethical model of the doctor–patient relationship begins and ends at the door of the clinic. After parents enter, and the paediatrician closes the door, they engage together in a confidential, private space. The paediatrician offers expert assessment and advice while parents share in decision-making. But as Delany et al point out in their timely paper,1 in our digital world, the walls of the contemporary consultation seem dangerously thin. A ‘crowd of voices’ potentially push into that hitherto private space offering novel opinions and options and sometimes making serious disagreements between health professionals and parents more likely or more difficult to manage. Or else families may choose to reach beyond the paediatrician’s office by sharing their child’s story (including potentially their experiences and views of the health professionals) with an online crowd. Delany et al provide a valuable framework and helpful...
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When is a 'decision an important decision in a decision tool
Apart from a global reduction in attendances during the COVID-19 pandemic,1 emergency departments continue to see growth in the presentations of children and young people (CYP).2 However, there has not been a similar increase in admissions leading to the so-called ‘needle in the haystack’ phenomenon which describes the difficulty clinicians face in selecting CYP for investigation or intervention when the incidence of modifiable disease is so low. CYP who present overtly unwell are always going to receive resuscitation regardless of the underlying cause of illness as restoration of adequate oxygenation, replenishment of circulating volume or support of cerebral function is a priority. These numbers, however, are small, likely no more than 1–2% of total attendances. A larger group of patients (perhaps 40% but with large regional and national variation) have a clinical appearance to healthcare professionals suggesting investigations are not necessary as they are deemed...
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Parents seeking treatment overseas
A medical couple living in England, neither of them citizens of the European Union (EU), recently crossed the Irish Sea. They arrived a week before their baby’s estimated day of delivery. After some days in a hotel, nature took its course... and they presented to an unsuspecting emergency department in Ireland. Their newborn boy was automatically eligible to apply for an EU passport: hardly the model of orderly antenatal care, but mission accomplished, with respect to his citizenship. Parents have a multiplicity of motives for seeking treatment of their child abroad; it is common for their infant boys to be circumcised for religious reasons in a country where this service is readily available, mirrored by adults who travel for dental veneers. These activities do not offend the law. Equally, parents may be presented with offers of treatments for their children that are unavailable in this country, encouraged by reports...
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